Pharmacologic Substance
zileuton Audio
[ zy-loo-tin ]
Brand Names:
Zyflo
Effect:
Bronchodilation; Decreased Capillary Permeability; Decreased Cellular Migration; Decreased Leukotriene Production
May Prevent:
Asthma
May Treat:
Asthma
More Information:
ChemID; DrugBank; DailyMed; DrugInfo; PDR
Definitions related to zileuton:
  • A substance that is used to prevent asthma symptoms and that is being studied in the prevention of lung cancer. It belongs to the family of drugs called leukotriene blockers.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • A synthetic derivative of hydroxyurea with antiasthmatic properties. The leukotriene inhibitor zileuton blocks 5-lipoxygenase, which catalyzes the formation of leukotrienes from arachidonic acid; causes bronchodilation; decreases bronchial mucous secretion and edema; and may prevent or decrease the symptoms of asthma. (NCI04)
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.